GDF3 antibody (AA 311-360)

Catalog No. ABIN8121827

This Rabbit Polyclonal antibody specifically detects GDF3 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for GDF3 antibody (AA 311-360) (ABIN8121827)

Target: GDF3 (Growth Differentiation Factor 3 (GDF3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDF3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GDF3 Antibody

Binding Specificity: AA 311-360

Purpose: GDF-3 Antibody

Specificity: GDF-3 Polyclonal Antibody detects endogenous levels of GDF-3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Growth/differentiation factor 3 at AA range: 311-360

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GDF3

Target: GDF3 (Growth Differentiation Factor 3 (GDF3))

Alternative Name: GDF-3

Background:

Synonyms: GDF3, Growth/differentiation factor 3, GDF-3

Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016],

Gene Name: GDF3

Protein Name: Growth/differentiation factor 3

Gene ID: 9573

UniProt: Q9NR23