G3BP1 antibody (AA 200-300)

Catalog No. ABIN8121835

The Mouse Monoclonal anti-G3BP1 antibody (Clone AB2382) (ABIN8121835) specifically detects G3BP1 in WB, IF and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for G3BP1 antibody (AA 200-300) (ABIN8121835)

Target: G3BP1 (GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This G3BP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA

Clone: AB2382

Product Details anti-G3BP1 Antibody

Binding Specificity: AA 200-300

Purpose: G3BP1 mouse mAb

Specificity: This antibody detects endogenous levels of G3BP1 protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 200 - 300 of the human G3BP1 protein.

Isotype: IgG

Application Details

Application Notes: WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for G3BP1

Target: G3BP1 (GTPase Activating Protein (SH3 Domain) Binding Protein 1 (G3BP1))

Alternative Name: G3BP1

Background:

Synonyms: Ras GTPase-activating protein-binding protein 1 (G3BP-1) (EC 3. 6. 4. 12) (EC 3. 6. 4. 13) (ATP-dependent DNA helicase VIII) (hDH VIII) (GAP SH3 domain-binding protein 1)

Background: G3BP stress granule assembly factor 1 (G3BP1) Homo sapiens This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008],

Gene Name: G3BP1 G3BP

Protein Name: G3BP1

Gene ID: 10146

UniProt: Q13283

Pathways: SARS-CoV-2 Protein Interactome