H2AFZ antibody (H2A.ZK7ac)

Catalog No. ABIN8121871

The Rabbit Polyclonal anti-H2AFZ antibody (ABIN8121871) specifically detects H2AFZ in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for H2AFZ antibody (H2A.ZK7ac) (ABIN8121871)

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This H2AFZ antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-H2AFZ Antibody

Binding Specificity: H2A.ZK7ac

Purpose: Histone H2A.Z (Acetyl Lys7) Antibody

Specificity: The antibody detects endogenous Histone H2A.Z (Acetyl Lys7) protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.

Immunogen: Synthetic Peptide of Histone H2A.Z (Acetyl Lys7)

Isotype: IgG

Application Details

Application Notes: WB 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, containing 0.5 % BSA, 0.02 % sodium azide as Preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for H2AFZ

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Alternative Name: Histone H2A.Z

Background:

Synonyms: H2AFZ, H2AZ, Histone H2A.Z, H2A/z

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008],

Gene Name: H2AFZ

Protein Name: Histone H2A.Z

Gene ID: 3015

UniProt: P0C0S5

Pathways: Telomere Maintenance