HMGA1 antibody (acLys15)

Catalog No. ABIN8121956

This Rabbit Polyclonal antibody specifically detects HMGA1 in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for HMGA1 antibody (acLys15) (ABIN8121956)

Target: HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HMGA1 Antibody

Binding Specificity: acLys15

Purpose: HMG-I/HMG-Y (Acetyl Lys15) Antibody

Specificity: This antibody detects endogenous levels of Human, Mouse, Rat HMG-I/HMG-Y (Acetyl Lys15)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human HMG-I/HMG-Y (Acetyl Lys15)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for HMGA1

Target: HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))

Alternative Name: HMG-I/HMG-Y

Background:

Synonyms: High mobility group protein HMG-I/HMG-Y (HMG-I(Y), High mobility group AT-hook protein 1, High mobility group protein A1, High mobility group protein R)

Background: This gene encodes a chromatin-associated protein involved in the regulation of gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of AT-rich regions in double-stranded DNA. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been identified on multiple chromosomes. [provided by RefSeq, Jan 2016],

Gene Name: HMGA1 HMGIY

Protein Name: HMG-I/HMG-Y (Acetyl Lys15)

Gene ID: 3159

UniProt: P17096

Pathways: Nuclear Hormone Receptor Binding, Autophagy