Histone H2A antibody (pSer129)

Catalog No. ABIN8122002

The Rabbit Polyclonal anti-Histone H2A antibody is suitable to detect Histone H2A in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for Histone H2A antibody (pSer129) (ABIN8122002)

Target: Histone H2A

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone H2A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Histone H2A Antibody

Binding Specificity: pSer129

Purpose: Histone H2A (Phospho Ser129) Antibody

Specificity: The antibody detects endogenous Histone H2A (Phospho Ser129) protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.

Immunogen: Synthetic Peptide of Histone H2A (Phospho Ser129)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, containing 0.5 % BSA, 0.02 % sodium azide as Preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Histone H2A

Target: Histone H2A

Background:

Synonyms: HIST1H2AG, H2AFP, HIST1H2AI, H2AFC, HIST1H2AK, H2AFD, HIST1H2AL, H2AFI, HIST1H2AM, H2AFN, Histone H2A type 1, H2A.1, Histone H2A/p, HIST2H2AA3, H2AFO, HIST2H2AA, HIST2H2AA4, Histone H2A type 2-A, Histone H2A.2, Histone H2A/o, HIST3H2A, Histone H2A type 3

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015],

Gene Name: HIST1H2AG/HIST1H2AI/HIST1H2AK/HIST1H2AL/HIST1H2AM/HIST2H2AA3/HIST2H2AA4/HIST3H2A

Protein Name: Histone H2A type 1/Histone H2A type 2/Histone H2A type 3

Gene ID: 8329, 8330, 8332

UniProt: P0C0S8