ITK antibody (AA 450-530)

Catalog No. ABIN8122156

The Rabbit Polyclonal anti-ITK antibody (ABIN8122156) specifically detects ITK in WB, IHC and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for ITK antibody (AA 450-530) (ABIN8122156)

Target: ITK (IL2-Inducible T-Cell Kinase (ITK))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ITK Antibody

Binding Specificity: AA 450-530

Purpose: ITK Antibody

Specificity: This antibody detects endogenous levels of human ITK

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human ITK AA range: 450-530

Isotype: IgG

Application Details

Application Notes: IHC 1:50-200, WB 1:500-2000. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for ITK

Target: ITK (IL2-Inducible T-Cell Kinase (ITK))

Alternative Name: ITK

Background:

Synonyms: Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2, Interleukin-2-inducible T-cell kinase, IL-2-inducible T-cell kinase, Kinase EMT, T-cell-specific kinase, Tyrosine-protein kinase Lyk)

Background: This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by RefSeq, Jul 2008],

Gene Name: ITK EMT LYK

Protein Name: ITK

Gene ID: 3702

UniProt: Q08881

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway