IGF2 antibody (AA 1-100)

Catalog No. ABIN8122236

The Rabbit Monoclonal anti-IGF2 antibody is suitable to detect IGF2 in samples from Human. It has been validated for IHC.

Quick Overview for IGF2 antibody (AA 1-100) (ABIN8122236)

Target: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IGF2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: AB1349

Product Details anti-IGF2 Antibody

Binding Specificity: AA 1-100

Purpose: IGF-2 Rabbit mAb (Ready to Use)

Specificity: The antibody can specifically recognize human IGF- 2 protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 1 - 100 of the human IGF - 2 protein.

Isotype: IgG

Application Details

Application Notes: It has been optimized for direct use, requiring no further dilution.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze

Storage: 4 °C

Storage Comment: Store at 4°C. Avoid freeze.

Target Details for IGF2

Target: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Alternative Name: IGF-2

Background:

Synonyms: C11orf43,IGF 2,IGF II,IGF-II,IGF2,IGF2_HUMAN,IGFII,INSIGF,insulin like growth factor 2 (somatomedin A) ,Insulin like Growth Factor 2,Insulin like growth factor II,Insulin like growth factor II precursor,Insulin like growth factor type 2,pp9974,Preptin,putative insulin like growth factor II associated protein,Somatomedin A,Somatomedin-A

Background: Insulin- like growth factor II (IGF- 2) is the protein hormones which belongs to the family of insulin- like growth factors that share structural similarity to insulin. It is secreted by the liver and circulates in the blood. In fetal, IGF- 2 is a major growth factor that regulating fetoplacental development influenced by placental lactogen. It is also involed in tissue differentiation. In adults, IGF- 2 is involved in glucose metabolism in liver, adipose tissue and skeletal muscle. It is an imprinted gene, expressed only from the paternal allele. Loss of imprinting is associated with Beckwith- Wiedemann syndrome.

Gene Name: IGF2

Protein Name: IGF-2

Gene ID: 3481

UniProt: P01344

Pathways: Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation