IGF2 antibody (AA 1-100)

Catalog No. ABIN8122238

This Mouse Monoclonal antibody specifically detects IGF2 in IHC. It exhibits reactivity toward Human.

Quick Overview for IGF2 antibody (AA 1-100) (ABIN8122238)

Target: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IGF2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: AB2338

Product Details anti-IGF2 Antibody

Binding Specificity: AA 1-100

Purpose: IGF-2 mouse mAb

Specificity: The antibody can specifically recognize human IGF-2 protein.

Purification: The antibody was purified by affinity chromatography using a specific immunogen.

Immunogen: A synthetic peptide corresponding to the amino acid region 1 - 100 of the human IGF - 2 protein.

Isotype: IgG

Application Details

Application Notes: IHC, 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for IGF2

Target: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Alternative Name: IGF-2

Background:

Synonyms: C11orf43, IGF 2, IGF II, IGF-II, IGF2, IGF2_HUMAN, IGFII, INSIGF, insulin like growth factor 2 (somatomedin A) , Insulin like Growth Factor 2, Insulin like growth factor II, Insulin like growth factor II precursor, Insulin like growth factor type 2, pp9974, Preptin, putative insulin like growth factor II associated protein, Somatomedin A, Somatomedin-A

Background: Insulin-like growth factor II (IGF-2) is the protein hormones which belongs to the family of insulin-like growth factors that share structural similarity to insulin. It is secreted by the liver and circulates in the blood. In fetal, IGF-2 is a major growth factor that regulating fetoplacental development influenced by placental lactogen. It is also involed in tissue differentiation. In adults, IGF-2 is involved in glucose metabolism in liver, adipose tissue and skeletal muscle. It is an imprinted gene, expressed only from the paternal allele. Loss of imprinting is associated with Beckwith-Wiedemann syndrome.

Gene Name: IGF2

Protein Name: IGF-2

Gene ID: 3481

UniProt: P01344

Pathways: Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation