IRF7 antibody (pSer471)

Catalog No. ABIN8122297

The Rabbit Polyclonal anti-IRF7 antibody (ABIN8122297) specifically detects IRF7 in WB and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for IRF7 antibody (pSer471) (ABIN8122297)

Target: IRF7 (Interferon Regulatory Factor 7 (IRF7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRF7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-IRF7 Antibody

Binding Specificity: pSer471

Purpose: IRF-7 (Phospho Ser471/472) Antibody

Specificity: This antibody detects endogenous levels of Human IRF-7 (phospho-Ser471 or 472) Mouse IRF-7 (phospho-Ser425 or 426), Rat IRF-7 (phospho-Ser423 or 424)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized phosho peptide around human IRF-7 (Ser471 and 472)

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for IRF7

Target: IRF7 (Interferon Regulatory Factor 7 (IRF7))

Alternative Name: IRF-7

Background:

Synonyms: Interferon regulatory factor 7 (IRF-7)

Background: IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established. [provided by RefSeq, Jul 2008],

Gene Name: IRF7

Protein Name: IRF-7 (Ser471/472)

Gene ID: 3665

UniProt: Q92985

Pathways: TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagy