IRF7 antibody (pSer477)

Catalog No. ABIN8122298

This Rabbit Polyclonal antibody specifically detects IRF7 in WB and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for IRF7 antibody (pSer477) (ABIN8122298)

Target: IRF7 (Interferon Regulatory Factor 7 (IRF7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRF7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-IRF7 Antibody

Binding Specificity: pSer477

Purpose: IRF-7 (Phospho Ser477) Antibody

Specificity: This antibody detects endogenous levels of Human IRF-7 (phospho-Ser477) ,Mouse IRF-7 (phospho-Ser431), Rat IRF-7 (phospho-Ser429)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized phosho peptide around human IRF-7 (Ser477)

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for IRF7

Target: IRF7 (Interferon Regulatory Factor 7 (IRF7))

Alternative Name: IRF-7

Background:

Synonyms: Interferon regulatory factor 7 (IRF-7)

Background: IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established. [provided by RefSeq, Jul 2008],

Gene Name: IRF7

Protein Name: IRF-7 (Ser477)

Gene ID: 3665

UniProt: Q92985

Pathways: TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagy