JAK2/3 antibody (pThr966, pTyr966)

Catalog No. ABIN8122382

This Rabbit Polyclonal antibody specifically detects JAK2/3 in WB, ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for JAK2/3 antibody (pThr966, pTyr966) (ABIN8122382)

Target: JAK2/3 (Janus Kinase 2/3 (JAK2/3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAK2/3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-JAK2/3 Antibody

Binding Specificity: pThr966, pTyr966

Purpose: JAK2/3 (Phospho Tyr966/939) Antibody

Specificity: This antibody detects endogenous levels of JAK2/3 (Phospho-Tyr966/939) Antibody at Human:Y966/939,Mouse:Y966/935,Rat:Y966/935, It doesn't reacte with total protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized Phospho peptide derived from human JAK2/3.at AA range: T966

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for JAK2/3

Target: JAK2/3 (Janus Kinase 2/3 (JAK2/3))

Alternative Name: JAK2/3

Background:

Synonyms: Tyrosine-protein kinase JAK2/JAK3 (EC 2.7.10.2) (Janus kinase 2/Janus kinase 3) (JAK-2/JAK-3)

Background: This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008],

Gene Name: JAK2 JAK3

Protein Name: JAK2/3

Gene ID: 1132

UniProt: O60674