KAT6B antibody (AA 1170-1250)

Catalog No. ABIN8122399

The Rabbit Polyclonal anti-KAT6B antibody (ABIN8122399) specifically detects KAT6B in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for KAT6B antibody (AA 1170-1250) (ABIN8122399)

Target: KAT6B (K(lysine) Acetyltransferase 6B (KAT6B))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KAT6B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-KAT6B Antibody

Binding Specificity: AA 1170-1250

Purpose: KAT6B Antibody

Specificity: KAT6B Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 1170-1250

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for KAT6B

Target: KAT6B (K(lysine) Acetyltransferase 6B (KAT6B))

Alternative Name: KAT6B

Background:

Background: The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012],

Gene Name: KAT6B KIAA0383 MORF MOZ2 MYST4

Protein Name: Histone acetyltransferase KAT6B (EC 2.3.1.48) (Histone acetyltransferase MOZ2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (MYST-4) (Monocytic leukemia zinc finger protein-related factor)

Gene ID: 23522

UniProt: Q8WYB5