KLKB1 antibody

Catalog No. ABIN8122408

The Rabbit Polyclonal anti-KLKB1 antibody (ABIN8122408) specifically detects KLKB1 in ELISA and WB. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for KLKB1 antibody (ABIN8122408)

Target: KLKB1 (Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLKB1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-KLKB1 Antibody

Purpose: APS Antibody

Specificity: APS Polyclonal Antibody detects endogenous levels of APS protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human APS.

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for KLKB1

Target: KLKB1 (Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1))

Alternative Name: APS

Background:

Synonyms: SH2B2; APS; SH2B adapter protein 2; Adapter protein with pleckstrin homology and Src homology 2 domains; SH2 and PH domain-containing adapter protein APS

Background: The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway. [provided by RefSeq, Jun 2009],

Gene Name: SH2B2

Protein Name: SH2B adapter protein 2

Gene ID: 10603

UniProt: O14492

Pathways: Complement System, Brown Fat Cell Differentiation