Cytokeratin 13 antibody (AA 400-458)

Catalog No. ABIN8122437

The Mouse Monoclonal anti-Cytokeratin 13 antibody is suitable to detect Cytokeratin 13 in samples from Human. It has been validated for IHC.

Quick Overview for Cytokeratin 13 antibody (AA 400-458) (ABIN8122437)

Target: Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cytokeratin 13 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: AB1253

Product Details anti-Cytokeratin 13 Antibody

Binding Specificity: AA 400-458

Purpose: Cytokeratin 13 mouse mAb

Specificity: The antibody can specifically recognize human CK13 protein.

Purification: The antibody was purified by affinity chromatography using a specific immunogen.

Immunogen: A synthetic peptide corresponding to the amino acid region 400 - 458 of the human Cytokeratin 13 protein.

Isotype: IgG

Application Details

Application Notes: IHC, 1:200-1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for Cytokeratin 13

Target: Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

Alternative Name: Cytokeratin 13

Background:

Synonyms: 47 kDa cytokeRatin, CK-13, CK13, Cytokeratin 13, CytokeRatin-13, K13, K1C13_HUMAN, Ka13, KeRatin 13, KeRatin, keRatin type I cytoskeletal 13, KeRatin-13, Krt-1. 13, Krt1-13, KRT13, MGC161462, MGC3781, type I cytoskeletal 13, Type I keRatin Ka13, WSN2

Background: Cytokeratin 13 (CK13) is a 54 kDa protein which belongs to the intermediate filament family. CK13 protein is highly expressed in normal tissues and gradually decreased or disappeared in malignant tissues. Defects in the CK13 gene may lead to white sponge nevus of cannon (WSN) , a rare autosomal dominant disorder which predominantly affects noncornified stratified squamous epithelia. CK13 can be used as an auxiliary indicator in the diagnosis of precancerous lesions.

Gene Name: KRT13

Protein Name: Cytokeratin 13

Gene ID: 3860

UniProt: P13646