LILRB3 antibody

Catalog No. ABIN8122636

The Rabbit Polyclonal anti-LILRB3 antibody (ABIN8122636) specifically detects LILRB3 in WB and ELISA. The antibody is reactive with Mouse and Human samples.

Quick Overview for LILRB3 antibody (ABIN8122636)

Target: LILRB3 (Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3))

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LILRB3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-LILRB3 Antibody

Purpose: LIRB3 Antibody

Specificity: LIRB3 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for LILRB3

Target: LILRB3 (Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3))

Alternative Name: LIRB3

Background:

Background: LILRB3 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. Leukocyte Immunoglobulin Like Receptor B3 belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: LILRB3 ILT5 LIR3

Protein Name: Leukocyte immunoglobulin-like receptor subfamily B member 3 (LIR-3) (Leukocyte immunoglobulin-like receptor 3) (CD85 antigen-like family member A) (Immunoglobulin-like transcript 5) (ILT-5) (Monocyte inhibitory receptor HL9) (CD antigen CD85a)

Gene ID: 11025

UniProt: O75022