LRP5 antibody (AA 1047-1097)

Catalog No. ABIN8122678

The Rabbit Polyclonal anti-LRP5 antibody (ABIN8122678) specifically detects LRP5 in WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for LRP5 antibody (AA 1047-1097) (ABIN8122678)

Target: LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRP5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LRP5 Antibody

Binding Specificity: AA 1047-1097

Purpose: LRP5 Antibody

Specificity: This antibody detects endogenous levels of LRP5 at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human LRP5 AA range: 1047-1097

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for LRP5

Target: LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))

Alternative Name: LRP5

Background:

Background: This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014],

Gene Name: LRP5 LR3 LRP7

Protein Name: LRP5

Gene ID: 4041

UniProt: O75197

Pathways: WNT Signaling, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation