KDM4C antibody (AA 737-787)

Catalog No. ABIN8122716

The Rabbit Polyclonal anti-KDM4C antibody is suitable to detect KDM4C in samples from Human and Mouse. It has been validated for WB and IHC.

Quick Overview for KDM4C antibody (AA 737-787) (ABIN8122716)

Target: KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM4C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-KDM4C Antibody

Binding Specificity: AA 737-787

Purpose: KDM4C Antibody

Specificity: This antibody detects endogenous levels of KDM4C at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human KDM4C AA range: 737-787

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for KDM4C

Target: KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

Alternative Name: KDM4C

Background:

Background: This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated form. This enzymatic action regulates gene expression and chromosome segregation. Chromosomal aberrations and changes in expression of this gene may be found in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],

Gene Name: KDM4C GASC1 JHDM3C JMJD2C KIAA0780

Protein Name: KDM4C

Gene ID: 23081

UniProt: Q9H3R0

Pathways: Nuclear Hormone Receptor Binding, Warburg Effect