MARCO antibody (AA 380-460)

Catalog No. ABIN8122735

The Rabbit Polyclonal anti-MARCO antibody (ABIN8122735) specifically detects MARCO in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for MARCO antibody (AA 380-460) (ABIN8122735)

Target: MARCO (Macrophage Receptor with Collagenous Structure (MARCO))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARCO antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MARCO Antibody

Binding Specificity: AA 380-460

Purpose: MARCO Antibody

Specificity: MARCO Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 380-460

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MARCO

Target: MARCO (Macrophage Receptor with Collagenous Structure (MARCO))

Alternative Name: MARCO

Background:

Background: The protein encoded byThis gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. [provided by RefSeq, Jul 2008],

Gene Name: MARCO SCARA2

Protein Name: Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2)

Gene ID: 8685

UniProt: Q9UEW3

Pathways: Activation of Innate immune Response