Mast Cell Tryptase antibody (AA 200-275)

Catalog No. ABIN8122770

The Rabbit Monoclonal anti-Mast Cell Tryptase antibody is suitable to detect Mast Cell Tryptase in samples from Human. It has been validated for IHC.

Quick Overview for Mast Cell Tryptase antibody (AA 200-275) (ABIN8122770)

Target: Mast Cell Tryptase

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Mast Cell Tryptase antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: AB1378

Product Details anti-Mast Cell Tryptase Antibody

Binding Specificity: AA 200-275

Purpose: Mast cell tryptase Rabbit mAb (Ready to Use)

Specificity: The antibody can specifically recognize human Mast cell tryptase protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 200 - 275 of the human Mast cell tryptase protein.

Isotype: IgG

Application Details

Application Notes: It has been optimized for direct use, requiring no further dilution.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze

Storage: 4 °C

Storage Comment: Store at 4°C. Avoid freeze.

Target Details for Mast Cell Tryptase

Target: Mast Cell Tryptase

Background:

Synonyms: alpha II,Lung tryptase,Mast cell alpha II tryptase,Mast cell beta I tryptase,Mast cell protease 7,Mast cell protease II,MCP 7,Pituitary tryptase,Skin tryptase,TPS 1,TPS1,TPS2,TPSAB1,TPSAB1 protein,TPSB1,Tryptase 1,Tryptase alpha 1,tryptase alpha I included,Tryptase alpha II,tryptase alpha II included,tryptase alpha included,tryptase alpha/beta 1,Tryptase beta 1,tryptase beta I included,Tryptase I,tryptase I included,Tryptase III,Tryptase skin

Background: Mast cell tryptase is the main neutral protease secreted by mast cells. It is the main component of mast cell secretory granules. It is the most abundant protein in mast cells, accounting for more than 50 % of the total protein of mast cell secretory granules. It is widely distributed in respiratory tract, gastrointestinal tract, skin and other tissues. It plays an important role in the pathological process of inflammatory diseases such as cell infection and injury, especially bronchoconstrictive asthma. It is used in the study of respiratory and gastrointestinal diseases.

Gene Name: TPSAB1

Protein Name: Mast cell tryptase

Gene ID: 7177

UniProt: Q15661