MSH2 antibody

Catalog No. ABIN8122950

The Mouse Monoclonal anti-MSH2 antibody is suitable to detect MSH2 in samples from Human. It has been validated for WB and IHC.

Quick Overview for MSH2 antibody (ABIN8122950)

Target: MSH2 (Mismatch Repair Protein 2 (MSH2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MSH2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: AB1240

Product Details anti-MSH2 Antibody

Purpose: MSH2 mouse mAb

Specificity: This antibody detects endogenous levels of MSH2 protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogen: Recombinant protein of the human MSH2 protein.

Isotype: IgG

Application Details

Application Notes: IHC, 1:100-1:400 | WB, 1:2000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for MSH2

Target: MSH2 (Mismatch Repair Protein 2 (MSH2))

Alternative Name: MSH2

Background:

Synonyms: DNA mismatch repair protein Msh2, MutS protein homolog 2, MSH2, hMSH2

Background: This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012],

Gene Name: MSH2

Protein Name: MutS Protein Homolog 2

Gene ID: 3662

UniProt: P43246

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response