MRPL49 antibody (AA 10-90)

Catalog No. ABIN8122968

The Rabbit Polyclonal anti-MRPL49 antibody is suitable to detect MRPL49 in samples from Human, Mouse and Rat. It has been validated for ELISA, WB, IHC and IF.

Quick Overview for MRPL49 antibody (AA 10-90) (ABIN8122968)

Target: MRPL49 (Mitochondrial Ribosomal Protein L49 (MRPL49))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL49 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MRPL49 Antibody

Binding Specificity: AA 10-90

Purpose: MRP-L49 Antibody

Specificity: MRP-L49 Polyclonal Antibody detects endogenous levels of MRP-L49 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from MRP-L49 . at AA range: 10-90

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MRPL49

Target: MRPL49 (Mitochondrial Ribosomal Protein L49 (MRPL49))

Alternative Name: MRP-L49

Background:

Synonyms: MRPL49, C11orf4, NOF1, OK/SW-cl.67, 39S ribosomal protein L49, mitochondrial, L49mt, MRP-L49, Neighbor of FAU, NOF, Protein NOF1

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. Pseudogenes corresponding to this gene are found on chromosomes 5q and 8p. [provided by RefSeq, May 2011],

Gene Name: MRPL49

Protein Name: 39S ribosomal protein L49 mitochondrial

Gene ID: 740

UniProt: Q13405