MTIF2 antibody (AA 450-530)

Catalog No. ABIN8122975

The Rabbit Polyclonal anti-MTIF2 antibody (ABIN8122975) specifically detects MTIF2 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for MTIF2 antibody (AA 450-530) (ABIN8122975)

Target: MTIF2 (Mitochondrial Translational Initiation Factor 2 (MTIF2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTIF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MTIF2 Antibody

Binding Specificity: AA 450-530

Purpose: IF2M Antibody

Specificity: IF2M Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 450-530

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MTIF2

Target: MTIF2 (Mitochondrial Translational Initiation Factor 2 (MTIF2))

Alternative Name: IF2M

Background:

Background: During the initiation of protein biosynthesis, initiation factor-2 (IF-2) promotes the binding of the initiator tRNA to the small subunit of the ribosome in a GTP-dependent manner. Prokaryotic IF-2 is a single polypeptide, while eukaryotic cytoplasmic IF-2 (eIF-2) is a trimeric protein. Bovine liver mitochondria contain IF-2(mt), an 85-kD monomeric protein that is equivalent to prokaryotic IF-2. The predicted 727-amino acid human protein contains a 29-amino acid presequence. Human IF-2(mt) shares 32 to 38 % amino acid sequence identity with yeast IF-2(mt) and several prokaryotic IF-2s, with the greatest degree of conservation in the G domains of the proteins. [provided by RefSeq, Mar 2016],

Gene Name: MTIF2

Protein Name: Translation initiation factor IF-2, mitochondrial (IF-2(Mt)) (IF-2Mt) (IF2(mt))

Gene ID: 4528

UniProt: P46199

Pathways: Ribonucleoprotein Complex Subunit Organization