MAP3K14 antibody (AA 90-170)

Catalog No. ABIN8123017

The Rabbit Polyclonal anti-MAP3K14 antibody (ABIN8123017) specifically detects MAP3K14 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for MAP3K14 antibody (AA 90-170) (ABIN8123017)

Target: MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP3K14 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MAP3K14 Antibody

Binding Specificity: AA 90-170

Purpose: M3K14 Antibody

Specificity: M3K14 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 90-170

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MAP3K14

Target: MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))

Alternative Name: M3K14

Background:

Background: This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008],

Gene Name: MAP3K14 NIK

Protein Name: Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF-kappa-beta-inducing kinase) (HsNIK) (Serine/threonine-protein kinase NIK)

Gene ID: 9020

UniProt: Q99558

Pathways: NF-kappaB Signaling, TCR Signaling