MAX antibody (pSer11)

Catalog No. ABIN8123093

This Rabbit Polyclonal antibody specifically detects MAX in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MAX antibody (pSer11) (ABIN8123093)

Target: MAX (MYC Associated Factor X (MAX))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAX antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MAX Antibody

Binding Specificity: pSer11

Purpose: MAX (Phospho Ser11) Antibody

Specificity: This antibody detects endogenous levels of Human,Mouse,Rat MAX (Phospho Ser11)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human MAX (Phospho Ser11)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MAX

Target: MAX (MYC Associated Factor X (MAX))

Alternative Name: MAX

Background:

Synonyms: Protein max (Class D basic helix-loop-helix protein 4, bHLHd4, Myc-associated factor X)

Background: The protein encoded byThis gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],

Gene Name: MAX BHLHD4

Protein Name: MAX (Phospho Ser11)

Gene ID: 4149

UniProt: P61244

Pathways: Mitotic G1-G1/S Phases