MYOD1 antibody (AA 100-200)

Catalog No. ABIN8123130

The Rabbit Monoclonal anti-MYOD1 antibody is suitable to detect MYOD1 in samples from Human. It has been validated for IHC.

Quick Overview for MYOD1 antibody (AA 100-200) (ABIN8123130)

Target: MYOD1 (Myogenic Differentiation 1 (MYOD1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MYOD1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: AB1299

Product Details anti-MYOD1 Antibody

Binding Specificity: AA 100-200

Purpose: MyoD1 Rabbit mAb (Ready to Use)

Specificity: The antibody can recognize human MyoD1 protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 100 - 200 of the human MyoD1 protein.

Isotype: IgG

Application Details

Application Notes: It has been optimized for direct use, requiring no further dilution.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze

Storage: 4 °C

Storage Comment: Store at 4°C. Avoid freeze.

Target Details for MYOD1

Target: MYOD1 (Myogenic Differentiation 1 (MYOD1))

Alternative Name: MyoD1

Background:

Synonyms: Myoblast determination protein 1,Class C basic helix-loop-helix protein 1 (bHLHc1) ,Myogenic factor 3 (Myf-3) ,MYOD1

Background: MyoD1 is a phosphorylated protein with a molecular weight of 45 kDa, which binds to myosin in the cytoskeleton. It is only expressed in embryonic rhabdomyosarcoma cells, but not in normal adult rhabdomyosarcoma cells. It is a marker of rhabdomyosarcoma and is often used in combination with Myogenin in rhabdomyosarcoma. A few non- myogenic tissues including adenoepithelium, neuroblastoma, Ewing's sarcoma, alveolar soft tissue sarcoma and rhabdomyosarcoma showed positive cytoplasm.

Gene Name: MYOD1 BHLHC1 MYF3 MYOD

Protein Name: MyoD1

Gene ID: 4654

UniProt: P15172

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development