Myosin 9 antibody (pSer1943)

Catalog No. ABIN8123137

The Rabbit Polyclonal anti-Myosin 9 antibody (ABIN8123137) specifically detects Myosin 9 in WB and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Myosin 9 antibody (pSer1943) (ABIN8123137)

Target: Myosin 9 (MYH9)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myosin 9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Myosin 9 Antibody

Binding Specificity: pSer1943

Purpose: Myosin IIa (Phospho Ser1943) Antibody

Specificity: This antibody detects endogenous levels of Human Myosin IIa (phospho-Ser1943)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized phosho peptide around human Myosin IIa (Ser1943)

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Myosin 9

Target: Myosin 9 (MYH9)

Alternative Name: Myosin IIa

Background:

Synonyms: Myosin-9 (Cellular myosin heavy chain, type A) (Myosin heavy chain 9) (Myosin heavy chain, non-muscle IIa) (Non-muscle myosin heavy chain A) (NMMHC-A) (Non-muscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA)

Background: This gene encodes a conventional non-muscle myosin, this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness. [provided by RefSeq, Dec 2011],

Gene Name: MYH9

Protein Name: Myosin IIa (Ser1943)

Gene ID: 4627

UniProt: P35579

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Integrin Complex