Myosin VI antibody (AA 40-120)

Catalog No. ABIN8123160

The Rabbit Polyclonal anti-Myosin VI antibody is suitable to detect Myosin VI in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for Myosin VI antibody (AA 40-120) (ABIN8123160)

Target: Myosin VI (MYO6)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myosin VI antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Myosin VI Antibody

Binding Specificity: AA 40-120

Purpose: Myosin VI Antibody

Specificity: Myosin VI Polyclonal Antibody detects endogenous levels of Myosin VI protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Myosin VI . at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:5000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Myosin VI

Target: Myosin VI (MYO6)

Alternative Name: Myosin VI

Background:

Synonyms: MYO6, KIAA0389, Unconventional myosin-VI, Unconventional myosin-6

Background: myosin VI(MYO6) Homo sapiens This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014],

Gene Name: MYO6

Protein Name: Unconventional myosin-VI

Gene ID: 4646

UniProt: Q9UM54

Pathways: Sensory Perception of Sound, Dicarboxylic Acid Transport, Asymmetric Protein Localization