NAGS antibody (AA 361-411)

Catalog No. ABIN8123189

This Rabbit Polyclonal antibody specifically detects NAGS in WB and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for NAGS antibody (AA 361-411) (ABIN8123189)

Target: NAGS (N-Acetylglutamate Synthase (NAGS))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAGS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NAGS Antibody

Binding Specificity: AA 361-411

Purpose: NAGS Antibody

Specificity: This antibody detects endogenous levels of NAGS at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human NAGS AA range: 361-411

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for NAGS

Target: NAGS (N-Acetylglutamate Synthase (NAGS))

Alternative Name: NAGS

Background:

Background: The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia. [provided by RefSeq, Jul 2008],

Gene Name: NAGS

Protein Name: NAGS

Gene ID: 162417

UniProt: Q8N159