NDRG1 antibody (pThr346)

Catalog No. ABIN8123207

This Rabbit Polyclonal antibody specifically detects NDRG1 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for NDRG1 antibody (pThr346) (ABIN8123207)

Target: NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDRG1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NDRG1 Antibody

Binding Specificity: pThr346

Purpose: NDRG1 (Phospho Thr346) Antibody

Specificity: This antibody detects endogenous levels of Human Mouse Rat NDRG1 (phospho-Thr346)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized phosho peptide around human NDRG1 (Thr346)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for NDRG1

Target: NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))

Alternative Name: NDRG1

Background:

Synonyms: Protein NDRG1 (Differentiation-related gene 1 protein) (DRG-1) (N-myc downstream-regulated gene 1 protein) (Nickel-specific induction protein Cap43) (Reducing agents and tunicamycin-responsive protein) (RTP) (Rit42)

Background: This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily.The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012],

Gene Name: NDRG1 CAP43 DRG1 RTP

Protein Name: NDRG1 (Thr346)

Gene ID: 10397

UniProt: Q92597