SGSH antibody

Catalog No. ABIN8123211

The Rabbit Monoclonal anti-SGSH antibody is suitable to detect SGSH in samples from Human. It has been validated for WB, IHC, ICC and IF.

Quick Overview for SGSH antibody (ABIN8123211)

Target: SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SGSH antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: AB2262

Product Details anti-SGSH Antibody

Purpose: SGSH Rabbit mAb

Specificity: This antibody detects endogenous levels of SGSH protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotype: IgG

Application Details

Application Notes: WB, 1:1000-1:5000 | IHC, 1:100-1:300 | IF, 1:100-1:300 |

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for SGSH

Target: SGSH (N-Sulfoglucosamine Sulfohydrolase (SGSH))

Alternative Name: SGSH

Background:

Synonyms: SGSH, HSS, N-sulphoglucosamine sulphohydrolase , Sulfoglucosamine sulfamidase, Sulphamidase,

Background: This gene encodes the enzyme sulfamidase, one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in this gene are associated with the lysosomal storage disease mucopolysaccaridosis IIIA, also known as Sanfilippo syndrome A, which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but their biological validity has not been determined. [provided by RefSeq, Jun 2017]

Gene Name: SGSH, HSS

Protein Name: SGSH

Gene ID: 6448

UniProt: P51688

Pathways: Glycosaminoglycan Metabolic Process