NTAN1 antibody (AA 83-133)

Catalog No. ABIN8123212

The Rabbit Polyclonal anti-NTAN1 antibody (ABIN8123212) specifically detects NTAN1 in WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for NTAN1 antibody (AA 83-133) (ABIN8123212)

Target: NTAN1 (N-terminal Asparagine Amidase (NTAN1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NTAN1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NTAN1 Antibody

Binding Specificity: AA 83-133

Purpose: NTAN1 Antibody

Specificity: This antibody detects endogenous levels of NTAN1 at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human NTAN1 AA range: 83-133

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for NTAN1

Target: NTAN1 (N-terminal Asparagine Amidase (NTAN1))

Alternative Name: NTAN1

Background:

Background: The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012],

Gene Name: NTAN1

Protein Name: NTAN1

Gene ID: 123803

UniProt: Q96AB6