NDE1 antibody (AA 270-350)

Catalog No. ABIN8123253

The Rabbit Polyclonal anti-NDE1 antibody is suitable to detect NDE1 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for NDE1 antibody (AA 270-350) (ABIN8123253)

Target: NDE1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDE1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NDE1 Antibody

Binding Specificity: AA 270-350

Purpose: NDE1 Antibody

Specificity: NDE1 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 270-350

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for NDE1

Target: NDE1

Alternative Name: NDE1

Background:

Background: This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012],

Gene Name: NDE1 NUDE

Protein Name: Nuclear distribution protein nudE homolog 1 (NudE)

Gene ID: 54820

UniProt: Q9NXR1