Neurotrophin 3 antibody (AA 180-230)

Catalog No. ABIN8123320

The Rabbit Polyclonal anti-Neurotrophin 3 antibody (ABIN8123320) specifically detects Neurotrophin 3 in IHC, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Neurotrophin 3 antibody (AA 180-230) (ABIN8123320)

Target: Neurotrophin 3 (NTF3)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neurotrophin 3 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Neurotrophin 3 Antibody

Binding Specificity: AA 180-230

Purpose: NT-3 Antibody

Specificity: The antibody detects endogenous NT-3

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic peptide from human protein at AA range: 180-230

Isotype: IgG

Application Details

Application Notes: IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Neurotrophin 3

Target: Neurotrophin 3 (NTF3)

Alternative Name: NT-3

Background:

Synonyms: Neurotrophin-3 (NT-3, HDNF, Nerve growth factor 2, NGF-2, Neurotrophic factor)

Background: The protein encoded byThis gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. [provided by RefSeq, Jul 2008],

Gene Name: NTF3

Protein Name: Neurotrophin-3 (NT-3) (HDNF) (Nerve growth factor 2) (NGF-2) (Neurotrophic factor)

Gene ID: 4908

UniProt: P20783

Pathways: RTK Signaling, Neurotrophin Signaling Pathway