NKX6-1 antibody (AA 180-260)

Catalog No. ABIN8123354

This Rabbit Polyclonal antibody specifically detects NKX6-1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for NKX6-1 antibody (AA 180-260) (ABIN8123354)

Target: NKX6-1 (NK6 Homeobox 1 (NKX6-1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKX6-1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NKX6-1 Antibody

Binding Specificity: AA 180-260

Purpose: Nkx-6.1 Antibody

Specificity: Nkx-6.1 Polyclonal Antibody detects endogenous levels of Nkx-6.1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Nkx-6.1 . at AA range: 180-260

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for NKX6-1

Target: NKX6-1 (NK6 Homeobox 1 (NKX6-1))

Alternative Name: Nkx-6.1

Background:

Synonyms: NKX6-1, NKX6A, Homeobox protein Nkx-6.1, Homeobox protein NK-6 homolog A

Background: In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM, Mar 2008],

Gene Name: NKX6-1

Protein Name: Homeobox protein Nkx-6.1

Gene ID: 4825

UniProt: P78426

Pathways: Dopaminergic Neurogenesis, Positive Regulation of Peptide Hormone Secretion