NUMB antibody (pSer276)

Catalog No. ABIN8123492

This Rabbit Polyclonal antibody specifically detects NUMB in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for NUMB antibody (pSer276) (ABIN8123492)

Target: NUMB (Numb Homolog (NUMB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUMB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NUMB Antibody

Binding Specificity: pSer276

Purpose: Numb (Phospho Ser276) Antibody

Specificity: This antibody detects endogenous levels of Human Numb (phospho-Ser276)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized phosho peptide around human Numb (Ser276)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for NUMB

Target: NUMB (Numb Homolog (NUMB))

Alternative Name: Numb

Background:

Synonyms: Protein numb homolog (h-Numb) (Protein S171)

Background: The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],

Gene Name: NUMB

Protein Name: Numb (Ser276)

Gene ID: 8650

UniProt: P49757

Pathways: Cell-Cell Junction Organization