NUMB antibody

Catalog No. ABIN8123493

The Rabbit Polyclonal anti-NUMB antibody is suitable to detect NUMB in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IF.

Quick Overview for NUMB antibody (ABIN8123493)

Target: NUMB (Numb Homolog (NUMB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUMB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-NUMB Antibody

Purpose: NUMB Antibody

Specificity: NUMB Polyclonal Antibody detects endogenous levels of NUMB protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human NUMB.

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000, IF ICC 1:100-500,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for NUMB

Target: NUMB (Numb Homolog (NUMB))

Alternative Name: NUMB

Background:

Synonyms: NUMB, Protein numb homolog, h-Numb, Protein S171

Background: The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],

Gene Name: NUMB

Protein Name: Protein numb homolog

Gene ID: 8650

UniProt: P49757

Pathways: Cell-Cell Junction Organization