Nyctalopin antibody (AA 139-189)

Catalog No. ABIN8123495

This Rabbit Polyclonal antibody specifically detects Nyctalopin in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for Nyctalopin antibody (AA 139-189) (ABIN8123495)

Target: Nyctalopin (NYX)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nyctalopin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Nyctalopin Antibody

Binding Specificity: AA 139-189

Purpose: NYX Antibody

Specificity: This antibody detects endogenous levels of NYX at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human NYX AA range: 139-189

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Nyctalopin

Target: Nyctalopin (NYX)

Alternative Name: NYX

Background:

Background: The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB. [provided by RefSeq, Oct 2008],

Gene Name: NYX CLRP

Protein Name: NYX

Gene ID: 60506

UniProt: Q9GZU5