OLIG2 antibody (AA 1-100)

Catalog No. ABIN8123511

The Mouse Monoclonal anti-OLIG2 antibody is suitable to detect OLIG2 in samples from Human and Mouse. It has been validated for WB, ELISA and IF.

Quick Overview for OLIG2 antibody (AA 1-100) (ABIN8123511)

Target: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This OLIG2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: AB2376

Product Details anti-OLIG2 Antibody

Binding Specificity: AA 1-100

Purpose: OLIG2 mouse mAb

Specificity: This antibody detects endogenous levels of OLIG2 protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 1 - 100 of the human OLIG2 protein.

Isotype: IgG

Application Details

Application Notes: WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for OLIG2

Target: OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

Alternative Name: OLIG2

Background:

Synonyms: Oligodendrocyte transcription factor 2, Oligo2, Class B basic helix-loop-helix protein 1 (bHLHb1) , Class E basic helix-loop-helix protein 19 (bHLHe19) , Protein kinase C-binding protein 2, Protein kinase C-binding protein RACK17, BHLHB1, BHLHE19, PRKCBP2, RACK17

Background: This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t (14,21) (q11. 2,q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq, Jul 2008],

Gene Name: OLIG2

Protein Name: OLIG2

Gene ID: 10215

UniProt: Q13516