OTUB1 antibody (AA 20-100)

Catalog No. ABIN8123533

The Rabbit Polyclonal anti-OTUB1 antibody (ABIN8123533) specifically detects OTUB1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for OTUB1 antibody (AA 20-100) (ABIN8123533)

Target: OTUB1 (OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OTUB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-OTUB1 Antibody

Binding Specificity: AA 20-100

Purpose: Otubain-1 Antibody

Specificity: Otubain-1 Polyclonal Antibody detects endogenous levels of Otubain-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Otubain-1 . at AA range: 20-100

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for OTUB1

Target: OTUB1 (OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))

Alternative Name: Otubain-1

Background:

Synonyms: OTUB1, OTB1, OTU1, HSPC263, Ubiquitin thioesterase OTUB1, Deubiquitinating enzyme OTUB1, OTU domain-containing ubiquitin aldehyde-binding protein 1, Otubain-1, hOTU1, Ubiquitin-specific-processing protease OTUB1

Background: OTU deubiquitinase, ubiquitin aldehyde binding 1(OTUB1) Homo sapiens The product ofThis gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008],

Gene Name: OTUB1

Protein Name: Ubiquitin thioesterase OTUB1

Gene ID: 55611

UniProt: Q96FW1