P-Cadherin antibody

Catalog No. ABIN8123546

This Rabbit Polyclonal antibody specifically detects P-Cadherin in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for P-Cadherin antibody (ABIN8123546)

Target: P-Cadherin (CDH3)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P-Cadherin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-P-Cadherin Antibody

Purpose: CDH3 Antibody

Specificity: This antibody detects endogenous levels of CDH3.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human CDH3 Polyclonal

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000, ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for P-Cadherin

Target: P-Cadherin (CDH3)

Alternative Name: CDH3

Background:

Synonyms: Cadherin-3 (Placental cadherin) (P-cadherin)

Background: This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). [provided by RefSeq, Nov 2015],

Gene Name: CDH3 CDHP

Protein Name: Cadherin-3 (Placental cadherin) (P-cadherin)

Gene ID: 1001

UniProt: P22223