PHOX2B antibody (AA 140-220)

Catalog No. ABIN8123575

The Rabbit Polyclonal anti-PHOX2B antibody (ABIN8123575) specifically detects PHOX2B in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for PHOX2B antibody (AA 140-220) (ABIN8123575)

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHOX2B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PHOX2B Antibody

Binding Specificity: AA 140-220

Purpose: PHX2B Antibody

Specificity: PHX2B Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 140-220

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PHOX2B

Target: PHOX2B (Paired-Like Homeobox 2b (PHOX2B))

Alternative Name: PHX2B

Background:

Background: paired like homeobox 2b(PHOX2B) Homo sapiens The DNA-associated protein encoded byThis gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome. [provided by RefSeq, Jul 2016],

Gene Name: PHOX2B PMX2B

Protein Name: Paired mesoderm homeobox protein 2B (Neuroblastoma Phox) (NBPhox) (PHOX2B homeodomain protein) (Paired-like homeobox 2B)

Gene ID: 8929

UniProt: Q99453