PON3 antibody

Catalog No. ABIN8123595

The Rabbit Polyclonal anti-PON3 antibody is suitable to detect PON3 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for PON3 antibody (ABIN8123595)

Target: PON3 (Paraoxonase 3 (PON3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PON3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PON3 Antibody

Purpose: PON3 Antibody

Specificity: PON3 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PON3

Target: PON3 (Paraoxonase 3 (PON3))

Alternative Name: PON3

Background:

Background: This gene is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. The encoded protein is secreted into the bloodstream and associates with high-density lipoprotein (HDL). The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein (LDL), a function that is believed to slow the initiation and progression of atherosclerosis. Alternatively spliced variants which encode different protein isoforms have been described, however, only one has been fully characterized. [provided by RefSeq, Jul 2008],

Gene Name: PON3

Protein Name: Serum paraoxonase/lactonase 3 (EC 3.1.1.2) (EC 3.1.1.81) (EC 3.1.8.1)

Gene ID: 5446

UniProt: Q15166

Pathways: Monocarboxylic Acid Catabolic Process