Phospholipase D2 antibody (AA 110-190)

Catalog No. ABIN8123619

The Rabbit Polyclonal anti-Phospholipase D2 antibody is suitable to detect Phospholipase D2 in samples from Human, Rat and Mouse. It has been validated for WB, ELISA and IHC.

Quick Overview for Phospholipase D2 antibody (AA 110-190) (ABIN8123619)

Target: Phospholipase D2 (PLD2)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phospholipase D2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Phospholipase D2 Antibody

Binding Specificity: AA 110-190

Purpose: PC-PLD2 Antibody

Specificity: PC-PLD2 Polyclonal Antibody detects endogenous levels of PC-PLD2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from PC-PLD2 . at AA range: 110-190

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Phospholipase D2

Target: Phospholipase D2 (PLD2)

Alternative Name: PC-PLD2

Background:

Synonyms: PLD2, Phospholipase D2, PLD 2, hPLD2, Choline phosphatase 2, PLD1C, Phosphatidylcholine-hydrolyzing phospholipase D2

Background: The protein encoded by this gene catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4,5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and/or regulated secretion. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011],

Gene Name: PLD2

Protein Name: Phospholipase D2

Gene ID: 5338

UniProt: O14939

Pathways: RTK Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling