PCM1 antibody (AA 140-220)

Catalog No. ABIN8123652

The Rabbit Polyclonal anti-PCM1 antibody is suitable to detect PCM1 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for PCM1 antibody (AA 140-220) (ABIN8123652)

Target: PCM1 (Pericentriolar Material 1 (PCM1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PCM1 Antibody

Binding Specificity: AA 140-220

Purpose: PCM1 Antibody

Specificity: PCM1 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 140-220

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PCM1

Target: PCM1 (Pericentriolar Material 1 (PCM1))

Alternative Name: PCM1

Background:

Background: pericentriolar material 1(PCM1) Homo sapiens The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015],

Gene Name: PCM1

Protein Name: Pericentriolar material 1 protein (PCM-1) (hPCM-1)

Gene ID: 5108

UniProt: Q15154

Pathways: Stem Cell Maintenance, M Phase, Maintenance of Protein Location