Phosducin-Like antibody

Catalog No. ABIN8123685

The Rabbit Polyclonal anti-Phosducin-Like antibody is suitable to detect Phosducin-Like in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for Phosducin-Like antibody (ABIN8123685)

Target: Phosducin-Like (PDCL)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phosducin-Like antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Phosducin-Like Antibody

Purpose: PHLP1 Antibody

Specificity: PHLP1 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Phosducin-Like

Target: Phosducin-Like (PDCL)

Alternative Name: PHLP1

Background:

Background: PH domain and leucine rich repeat protein phosphatase 1(PHLPP1) Homo sapiens This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. [provided by RefSeq, Dec 2011],

Gene Name: PHLPP1 KIAA0606 PHLPP PLEKHE1 SCOP

Protein Name: PH domain leucine-rich repeat-containing protein phosphatase 1 (EC 3.1.3.16) (Pleckstrin homology domain-containing family E member 1) (PH domain-containing family E member 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP)

Gene ID: 23239

UniProt: O60346