PDE6D antibody (AA 89-139)

Catalog No. ABIN8123729

This Rabbit Polyclonal antibody specifically detects PDE6D in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for PDE6D antibody (AA 89-139) (ABIN8123729)

Target: PDE6D (phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE6D antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDE6D Antibody

Binding Specificity: AA 89-139

Purpose: PDE6D Antibody

Specificity: This antibody detects endogenous levels of PDE6D at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human PDE6D AA range: 89-139

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PDE6D

Target: PDE6D (phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D))

Alternative Name: PDE6D

Background:

Background: This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants. [provided by RefSeq, Mar 2014],

Gene Name: PDE6D PDED

Protein Name: PDE6D

Gene ID: 5147

UniProt: O43924