POLK antibody (AA 272-322)

Catalog No. ABIN8123854

The Rabbit Polyclonal anti-POLK antibody (ABIN8123854) specifically detects POLK in WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for POLK antibody (AA 272-322) (ABIN8123854)

Target: POLK (Polymerase (DNA Directed) kappa (POLK))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLK antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-POLK Antibody

Binding Specificity: AA 272-322

Purpose: POLK Antibody

Specificity: This antibody detects endogenous levels of POLK at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human POLK AA range: 272-322

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for POLK

Target: POLK (Polymerase (DNA Directed) kappa (POLK))

Alternative Name: POLK

Background:

Background: This gene encodes a member of the DNA polymerase type-Y family of proteins. The encoded protein is a specialized DNA polymerase that catalyzes translesion DNA synthesis, which allows DNA replication in the presence of DNA lesions. Human cell lines lacking a functional copy of this gene exhibit impaired genome integrity and enhanced susceptibility to oxidative damage. Mutations in this gene that impair enzyme activity may be associated with prostate cancer in human patients. [provided by RefSeq, Sep 2016],

Gene Name: POLK DINB1

Protein Name: POLK

Gene ID: 51426

UniProt: Q9UBT6

Pathways: DNA Damage Repair