ACTH antibody (AA 100-200)

Catalog No. ABIN8123995

The Rabbit Monoclonal anti-ACTH antibody (Clone AB1338) (ABIN8123995) specifically detects ACTH in IHC. The antibody is reactive with Human samples.

Quick Overview for ACTH antibody (AA 100-200) (ABIN8123995)

Target: ACTH (Adrenocorticotropic hormone (ACTH))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ACTH antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: AB1338

Product Details anti-ACTH Antibody

Binding Specificity: AA 100-200

Purpose: Adrenocorticotropin (ACTH) Rabbit mAb (Ready to Use)

Specificity: The antibody can specifically recognize human ACTH protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 100 - 200 of the human Adrenocorticotropin protein.

Isotype: IgG

Application Details

Application Notes: It has been optimized for direct use, requiring no further dilution.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze

Storage: 4 °C

Storage Comment: Store at 4°C. Avoid freeze.

Target Details for ACTH

Target: ACTH (Adrenocorticotropic hormone (ACTH))

Alternative Name: Adrenocorticotropin

Background:

Synonyms: ACTH,Adrenocorticotropic hormone,Adrenocorticotropin,alpha melanocyte stimulating hormone,Alpha MSH,Alpha-MSH,beta endorphin,Beta LPH,beta melanocyte stimulating hormone,Beta MSH,Beta-LPH,Beta-MSH,CLIP,Gamma MSH,Gamma-LPH,Gamma-MSH,Lipotropin beta,Lipotropin gamma,LPH,Melanotropin alpha,Melanotropin,Melanotropin beta,Melanotropin gamma,met enkephalin,MSH,NPP,POC,POMC,pro ACTH endorphin,Proopiomelanocortin,Proopiomelanocortin preproprotein

Background: ACTH is a polypeptide hormone secreted by anterior pituitary cells. ACTH effects adrenal gland to product of cortisol and it also mediates bone formation and osteoblast survival. ACTH antibody is mainly used for functional classification of pituitary tumors and differential diagnosis of primary and metastatic pituitary tumors. Studies have shown that abnormal ACTH products are often related to lung small cell carcinoma, so it can be used to detect the distribution of hormone cells in some neuroendocrine tumors, such as pheochromocytoma and carcinoid.

Gene Name: POMC

Protein Name: Adrenocorticotropin

Gene ID: 5443

UniProt: P01189

Pathways: Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity