PRC1 antibody (pThr481)

Catalog No. ABIN8124110

This Rabbit Polyclonal antibody specifically detects PRC1 in WB and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PRC1 antibody (pThr481) (ABIN8124110)

Target: PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PRC1 Antibody

Binding Specificity: pThr481

Purpose: PRC1(Phospho Thr481)Antibody

Specificity: The antibody detects endogenous PRC1Phospho occurs at Thr481

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic Phospho peptide from human protein at AA range: 481

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PRC1

Target: PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))

Alternative Name: PRC1

Background:

Synonyms: Protein regulator of cytokinesis 1

Background: This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012],

Gene Name: PRC1

Protein Name: Protein regulator of cytokinesis 1

Gene ID: 9055

UniProt: O43663