PROZ antibody (AA 141-190)

Catalog No. ABIN8124132

The Rabbit Polyclonal anti-PROZ antibody is suitable to detect PROZ in samples from Human, Mouse and Rat. It has been validated for WB and IHC.

Quick Overview for PROZ antibody (AA 141-190) (ABIN8124132)

Target: PROZ (Protein Z, Vitamin K-Dependent Plasma Glycoprotein (PROZ))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PROZ antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PROZ Antibody

Binding Specificity: AA 141-190

Purpose: PROZ Antibody

Specificity: This antibody detects endogenous levels of Human PROZ

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human PROZ AA range: 141-190

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PROZ

Target: PROZ (Protein Z, Vitamin K-Dependent Plasma Glycoprotein (PROZ))

Alternative Name: PROZ

Background:

Synonyms: Vitamin K-dependent protein Z

Background: This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012],

Gene Name: PROZ

Protein Name: PROZ

Gene ID: 8858

UniProt: P22891